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Zuclopenthixol CAS No. 53772-83-1 Pharmaceutical API

Product name

Zuclopenthixol

CAS No. 

53772-83-1

EINECS No.

258-758-5

Formula 

C22H25ClN2OS

Weight

400.96

Appearance

White to off-white Solid

Purity

≥ 98.00%

Type

Pharmaceutical API; Psychotropic Drug

    Product details

    CAS NO
    02

    introduce

    Zuclopenthixol is a potent antipsychotic pharmaceutical API and thioxanthene derivative, acting as a mixed dopamine D1/D2 receptor antagonist. It is mainly used for the treatment of schizophrenia, mania and other mental disorders.

    Our product complying with strict international pharmaceutical standards to ensure high purity, stable efficacy and reliable supply for clinical treatment and pharmaceutical formulation.
    Aprotinin CAS 9087-70-1 & 9004-04-0 外包装2
    02

    Physical and chemical properties

    Zuclopenthixol possesses key physical and chemical characteristics as follows:

    - Density: 1.289±0.06 g/cm3
    - Melting Point: 56-60 °C
    - Boiling Point: 577.4±50.0 °C
    - Flash Point: 303 °C
    - pKa: 14.96±0.10(Predicted)
    - Solubility: Slightly soluble in chloroform and methanol

    advantage

    Potent Antipsychotic Efficacy
    As a thioxanthene derivative, it acts as a mixed dopamine D1/D2 receptor antagonist. It exerts its effect by blocking dopamine and other receptors, effectively relieving positive and negative symptoms of schizophrenia (e.g., delusions, hallucinations, apathy).​

    High Targeted
    It has weak anticholinergic effect and strong antihistamine effect, especially suitable for psychiatric patients with anxiety and hallucinations. Compared with similar drugs with strong anticholinergic effect, its adverse reactions are milder.​​​​

    Good Tolerability
    Low acute and chronic toxicity under therapeutic doses, with no obvious toxicity to heart, liver and kidney; mild adverse reactions, suitable for long-term maintenance treatment.​​

    Wide Adaptability
    Effective for schizophrenia, mania, anxiety-related mental disorders and post-traumatic psychosis; especially suitable for elderly patients with good safety profile.​​

    aPPLICATION

    It is mainly used for the treatment of mental diseases, the specific applications include:​​

    Schizophrenia Treatment: ​​Used for acute and chronic schizophrenia, especially suitable for paranoid-hallucinatory type, hebephrenia and other types, as well as patients with hallucinations, delusions, thought disorders, excitement and restlessness and other symptoms. It can relieve symptoms and help prevent recurrence in convalescent patients.

    Other Psychiatric Treatments: ​​Used for manic episodes of bipolar disorder to relieve symptoms such as excitement and restlessness; it can also treat restlessness and confusion caused by mental factors, as well as mental illness caused by brain atrophy and trauma, delirium tremens, etc.

    Adjunctive and Potential Applications: ​​It can be used as an intermediate to synthesize its decanoate preparation, which is suitable for the maintenance treatment of chronic schizophrenia; it is also an inhibitor of coxsackievirus B3, with potential antiviral effect.​
    ​

    Quality Commitment

    We implement strict full-process quality inspection, with each batch of Zuclopenthixol undergoing rigorous testing on key indicators such as purity, solubility and impurity content to meet international pharmaceutical standards. Equipped with a stable raw material supply chain and advanced pharmaceutical-grade production facilities, we ensure continuous large-scale supply.

    Our professional technical team provides tailored services including formulation optimization, clinical application guidance and post-sales technical support for pharmaceutical enterprises, clinical institutions and research laboratories.

    in conclusion

    As a classic thioxanthene-derived antipsychotic API, Zuclopenthixol plays an irreplaceable core role in the clinical treatment of mental disorders with its potent efficacy, good tolerability, broad clinical applicability and clear pharmacological mechanism. It effectively relieves symptoms of various mental illnesses, improving patients’ quality of life and supporting the development of psychiatric medical care.

    With stable product quality, proven clinical performance, reliable supply capacity and professional technical services, we are committed to providing high-quality Zuclopenthixol API for global customers. Choose our Zuclopenthixol to meet your needs in pharmaceutical formulation, clinical treatment and biomedical research. Contact us for more product details and cooperation support.