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Sorafenib CAS No. 284461-73-0 Antineoplastic Pharmaceutical API
02
introduce
Sorafenib is a potent oral multikinase inhibitor and core antineoplastic API. It targets both tumor cell proliferation (RAF kinases) and angiogenesis (VEGFR, PDGFR) pathways, blocking cancer progression. Approved for advanced renal cell carcinoma, hepatocellular carcinoma, and thyroid cancer.
Our products comply with strict international standards to ensure high purity, stable efficacy, and reliable supply.
02
Physical and chemical properties
Sorafenib exhibits key physicochemical characteristics supporting its pharmaceutical and research applications, as follows:
- Melting Point: 202-204 °C
- Density: 1.5±0.1 g/cm³ (Predicted)
- Vapor Pressure: 0 Pa at 25 °C
- Storage Temperature: Sealed in dry condition; store at -20 °C in a freezer
- Solubility: Slightly soluble in chloroform and DMSO; practically insoluble in water (100 μg/L at 20 °C)
Multitargeted Mechanism
Inhibits RAF serine/threonine kinases and receptor tyrosine kinases (VEGFR, PDGFR, KIT, FLT-3), it can simultaneously achieve the dual effects of inhibiting tumor cell proliferation and blocking tumor angiogenesis, with a more comprehensive treatment range.
Inhibits RAF serine/threonine kinases and receptor tyrosine kinases (VEGFR, PDGFR, KIT, FLT-3), it can simultaneously achieve the dual effects of inhibiting tumor cell proliferation and blocking tumor angiogenesis, with a more comprehensive treatment range.
Widely Applicable
Approved for multiple solid tumors (renal cell carcinoma, hepatocellular carcinoma, thyroid cancer) and under investigation for other malignancies.
Clinically Proven Efficacy
Most patients have good tolerability after taking it, and adverse reactions are controllable. Extends overall survival and progression-free survival in advanced cancer patients, with a well-characterized safety profile.
Kidney Cancer Treatment
Used for the treatment of advanced renal cell carcinoma, it can improve the patient's condition, prolong progression-free survival, and improve quality of life, especially suitable for advanced renal cell carcinoma patients who failed previous systemic treatment.
Used for the treatment of advanced renal cell carcinoma, it can improve the patient's condition, prolong progression-free survival, and improve quality of life, especially suitable for advanced renal cell carcinoma patients who failed previous systemic treatment.
Liver Cancer Treatment
Used for the treatment of hepatocellular carcinoma, it inhibits the proliferation and angiogenesis of liver cancer cells through dual antineoplastic effects, controls tumor progression, and provides an effective treatment plan for liver cancer patients.
Thyroid Cancer Treatment
Used for the treatment of locally recurrent or metastatic thyroid carcinoma refractory to radioactive iodine treatment, blocking tumor development and relieving patient symptoms.
Other Potential Applications
Clinical trials are currently underway to explore its therapeutic effect on other tumors such as non-small cell lung cancer, metastatic breast cancer, and melanoma, and to study its efficacy in combination with other antineoplastic drugs.
We implement strict full-process quality control, with each batch of Sorafenib undergoing rigorous testing of key indicators including purity, solubility and impurity content to meet standards. Equipped with a stable raw material supply chain, we ensure continuous large-scale supply.
Our professional technical team provides tailored services, including formulation optimization, application guidance, and post-sales technical support to address clinical and production needs.
Our professional technical team provides tailored services, including formulation optimization, application guidance, and post-sales technical support to address clinical and production needs.
As a pioneering multikinase inhibitor, Sorafenib has transformed the treatment of advanced solid tumors by targeting dual key pathways of cancer progression. With its proven clinical efficacy, broad indication range, oral convenience, and reliable supply capacity, we are committed to providing high-quality Sorafenib API and professional services for global pharmaceutical companies, research institutions, and clinical applications.
Choose our Sorafenib to meet your needs in pharmaceutical formulation, anticancer research, and clinical treatment. Contact us for more product details and cooperation support.
Choose our Sorafenib to meet your needs in pharmaceutical formulation, anticancer research, and clinical treatment. Contact us for more product details and cooperation support.