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Sitagliptin Intermediates CAS NO 486459-71-6 Pharmaceutical Intermediates
02
introduce
As a leading integrated chemical manufacturer, we are committed to providing high quality Sitagliptin Monohydrochloride that meets the stringent requirements of the pharmaceutical industry. Our state-of-the-art production facilities and experienced team ensure that the products we deliver meet the highest quality standards. We understand the importance of a reliable supply chain and offer flexible solutions based on your specific needs.
02
Physical and chemical properties
Sitagliptin monohydrochloride (CAS No: 489461-61-6) is a potent DPP-4 inhibitor that plays an important role in the management of type 2 diabetes.
- Molecular formula: C16H16ClF6N5O
- Molecular weight: 443.78 g/mol
- Appearance: White to off-white crystalline powder
- Melting point: approx. 150-155 °C
- Solubility: Soluble in water and organic solvents, easy to formulate and process.
Sitagliptin monohydrochloride has a unique structure and possesses DPP-4 inhibitory activity, which enhances its effectiveness in controlling blood glucose levels, making it an important component of diabetes management.
There are several advantages to incorporating sitagliptin monohydrochloride into a pharmaceutical formulation:
1. Effective Blood Sugar Control: Sitagliptin is known for its ability to effectively lower blood sugar levels, making it a top choice for patients with type 2 diabetes.
2. Improve patient compliance: The oral formulation of sitagliptin monohydrochloride is convenient for patients to take and helps them adhere to the treatment plan.
3. Minimal side effects: Compared with other diabetes drugs, sitagliptin has a good safety profile and fewer gastrointestinal side effects.
4. Multiple Applications: This compound can be used in various formulations, including combination therapies, enhancing its utility in diabetes management.
Sitagliptin monohydrochloride is primarily used in the pharmaceutical industry for the synthesis of sitagliptin, which is used to treat type 2 diabetes. Its unique properties make it suitable for a variety of applications, including:
- Synthesis of Sitagliptin: The monohydrochloride form is a key component in the production of sitagliptin, which could aid in the development of effective diabetes treatments.
- Research and Development: Pharmaceutical researchers are using sitagliptin hydrochloride to develop new formulations and therapeutic strategies, particularly in the areas of endocrinology and metabolic disorders.
- Formulation Development: The compound can be incorporated into various dosage forms, including tablets and oral solutions, to improve patient compliance and therapeutic efficacy.
In summary, Sitagliptin monohydrochloride is a key ingredient for the pharmaceutical industry, offering numerous advantages for drug development and synthesis. With our expertise and commitment to quality, we are a trusted partner for all your chemistry needs. Contact us today to learn more about our products and how we can support your business in the growing pharmaceutical sector.




