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Semaglutide CAS No. 910463-68-2 Pharmaceutical Raw Material
02
introduce
introduce
Semaglutide is a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist and core pharmaceutical API, derived from human GLP-1 with structural modifications for prolonged half-life. It mimics GLP-1 physiological effects, regulating blood glucose and body weight. Approved for Type 2 Diabetes Mellitus (T2DM) and obesity management.
Our products comply with strict international standards to ensure high purity, stable efficacy, and reliable supply.
02
Physical and chemical properties
Semaglutide exhibits key physical and chemical characteristics supporting its pharmaceutical and research applications, as follows:
- Storage: -20 °C
- Solubility: Soluble in DMSO (3mg/mL)
- Storage: -20 °C
- Solubility: Soluble in DMSO (3mg/mL)
1. Outstanding Long-acting Property
As a GLP-1 analogue, it resists degradation by DPP-4 enzyme and enhances albumin binding affinity through structural optimization, thus significantly prolonging the half-life in vivo. It only needs to be injected once a week. Compared with similar daily-injection drugs such as liraglutide, it has a lower administration frequency and significantly improves patient compliance.
As a GLP-1 analogue, it resists degradation by DPP-4 enzyme and enhances albumin binding affinity through structural optimization, thus significantly prolonging the half-life in vivo. It only needs to be injected once a week. Compared with similar daily-injection drugs such as liraglutide, it has a lower administration frequency and significantly improves patient compliance.
2. Superior Efficacy in Hypoglycemia and Weight Loss
Its hypoglycemic effect is better than that of sitagliptin, exenatide, insulin glargine and other drugs, and it can more significantly reduce the glycated hemoglobin (HbA1c) level of patients with type 2 diabetes. Meanwhile, it can suppress appetite and delay gastric emptying.
Its hypoglycemic effect is better than that of sitagliptin, exenatide, insulin glargine and other drugs, and it can more significantly reduce the glycated hemoglobin (HbA1c) level of patients with type 2 diabetes. Meanwhile, it can suppress appetite and delay gastric emptying.
3. Wider Coverage of Multi-effects
It has the functions of hypoglycemia, weight loss, cardiovascular protection and renal protection. It can reduce the risk of major cardiovascular events in patients with type 2 diabetes complicated with cardiovascular disease, and delay the progression of nephropathy and cardiovascular death risk in patients with type 2 diabetes complicated with chronic kidney disease.
4. Flexible Dosage Form Options
It has both injectable and oral dosage forms. Compared with most GLP-1 analogues that can only be administered by injection, it adapts to the medication preferences of different patients and has a wider range of application scenarios.
It has both injectable and oral dosage forms. Compared with most GLP-1 analogues that can only be administered by injection, it adapts to the medication preferences of different patients and has a wider range of application scenarios.
5. Good Safety Profile
There are no clear reports of drug-related hepatotoxicity, and it has good tolerance. Compared with some hypoglycemic drugs that may cause liver and kidney burden, it has more guaranteed medication safety.
There are no clear reports of drug-related hepatotoxicity, and it has good tolerance. Compared with some hypoglycemic drugs that may cause liver and kidney burden, it has more guaranteed medication safety.
1. Core Indication
Used for the treatment of type 2 diabetes, regulating blood glucose levels and improving the disorder of glucose metabolism in patients with diet control and exercise intervention.
2. Weight Management Used for weight control in obese or overweight people, reducing calorie intake by suppressing appetite and slowing down gastric emptying rate to help reduce weight.
3. Cardiovascular Risk Prevention and Control Reduces the risk of major cardiovascular events in patients with type 2 diabetes complicated with cardiovascular disease; approved for obese or overweight adults to reduce their risk of serious heart disease.
4. Renal Protection Delays the progression of nephropathy in patients with type 2 diabetes complicated with chronic kidney disease and reduces the risk of cardiovascular death in such patients.
2. Weight Management Used for weight control in obese or overweight people, reducing calorie intake by suppressing appetite and slowing down gastric emptying rate to help reduce weight.
3. Cardiovascular Risk Prevention and Control Reduces the risk of major cardiovascular events in patients with type 2 diabetes complicated with cardiovascular disease; approved for obese or overweight adults to reduce their risk of serious heart disease.
4. Renal Protection Delays the progression of nephropathy in patients with type 2 diabetes complicated with chronic kidney disease and reduces the risk of cardiovascular death in such patients.
We implement strict full-process quality control, with each batch of Semaglutide undergoing rigorous testing of key indicators including purity, solubility, stability, peptide sequence integrity, and microbial contamination to meet standards.
Equipped with a stable raw material supply chain, we ensure continuous large-scale supply. Our professional technical team provides tailored services, including formulation optimization, reconstitution guidance, and post-sales technical support for clinical and production needs.
Equipped with a stable raw material supply chain, we ensure continuous large-scale supply. Our professional technical team provides tailored services, including formulation optimization, reconstitution guidance, and post-sales technical support for clinical and production needs.
As a leading GLP-1 receptor agonist, Semaglutide has revolutionized the treatment of Type 2 Diabetes Mellitus and obesity, offering long-acting efficacy, dual therapeutic benefits, and cardiovascular protection. With its exceptional quality, reliable supply capacity, and broad formulation adaptability, we are committed to providing high-quality Semaglutide API and professional services for global pharmaceutical companies, research institutions, and clinical applications.
Choose our Semaglutide to meet your needs in pharmaceutical formulation, metabolic disease research, and clinical treatment. Contact us for more product details and cooperation support.
Choose our Semaglutide to meet your needs in pharmaceutical formulation, metabolic disease research, and clinical treatment. Contact us for more product details and cooperation support.