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Pemetrexed Disodium CAS No.150399-23-8 Pharmaceutical Intermediates
02
introduce
Pemetrexed disodium is a potent antifolate chemotherapy drug that has been developed for the treatment of malignant pleural mesothelioma and non-small cell lung cancer (NSCLC). As a multi-target inhibitor of folate-dependent enzymes, pemetrexed disrupts the synthesis of nucleic acids and proteins, thereby inhibiting tumor cell growth. Our company specializes in the production, research and trading of pemetrexed disodium, ensuring that we meet the diverse needs of our pharmaceutical industry customers.
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Physical and chemical properties
Pemetrexed disodium is characterized by being a white to off-white crystalline powder. Its molecular weight is 451.41 g/mol and its melting point is about 200-210°C. The compound is soluble in water and exhibits good stability under various conditions, making it suitable for use in pharmaceutical preparations.
The unique structure of pemetrexed disodium includes a sulfonamide group and multiple functional groups, which enhance its ability to inhibit key enzymes of folate metabolism, such as thymidylate synthase, dihydrofolate reductase, and glycinamide nucleotide formyltransferase. This multi-target approach is critical to maximize its therapeutic effect and minimize drug resistance.
Pemetrexed disodium is mainly used to treat malignant pleural mesothelioma and non-small cell lung cancer (NSCLC). It is usually used in combination with cisplatin to enhance its efficacy and improve patient prognosis. Clinical studies have shown that pemetrexed can significantly prolong the progression-free survival and overall survival of patients with these malignant tumors.
In addition to its primary use, pemetrexed is also being studied for the treatment of other solid tumors, including breast cancer and colorectal cancer. Its ability to inhibit multiple pathways of tumor growth has made it a drug of interest in various therapeutic areas.
Pemetrexed disodium is mainly used to treat malignant pleural mesothelioma and non-small cell lung cancer (NSCLC). It is usually used in combination with cisplatin to enhance its efficacy and improve patient prognosis. Clinical studies have shown that pemetrexed can significantly prolong the progression-free survival and overall survival of patients with these malignant tumors.
In addition to its primary use, pemetrexed is also being studied for the treatment of other solid tumors, including breast cancer and colorectal cancer. Its ability to inhibit multiple pathways of tumor growth has made it a drug of interest in various therapeutic areas.
As an enterprise integrating production, R&D and trading, we are committed to providing customers with high-quality Pemetrexed Disodium. We adhere to strict quality control measures throughout the production process to ensure that our products meet international standards. Our state-of-the-art facilities are equipped with advanced technology, allowing us to produce Pemetrexed Disodium with high purity and consistent quality.
Our dedicated R&D team is constantly exploring new applications and synthesis methods for pemetrexed disodium, ensuring that we are always at the forefront of innovation in the pharmaceutical industry. We prioritize customer satisfaction and provide our customers with comprehensive technical support and logistical assistance to help them navigate the complexities of drug development.
In summary, pemetrexed disodium is an important therapeutic agent for the treatment of malignant pleural mesothelioma and non-small cell lung cancer, providing numerous benefits to patients facing these challenges. With its favorable physical and chemical properties, it is an effective solution to inhibit tumor growth and progression. Our company's commitment to quality, research and customer support makes us a reliable partner for businesses seeking high-quality pemetrexed disodium.
Whether you are involved in drug development or research, our products can help you achieve your goals in the evolving pharmaceutical landscape. To learn more about our pemetrexed disodium and how it can benefit your project, contact us today!