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Paricalcitol CAS No.131918-61-1 Pharmaceutical Intermediates
02
introduce
Paricalcitol is a synthetic analog of Vitamin D2 specifically developed for the treatment of secondary hyperparathyroidism, particularly in patients with chronic kidney disease (CKD). The compound is recognized for its ability to regulate parathyroid hormone (PTH) levels, thereby helping to maintain calcium and phosphorus balance in the body. Our company specializes in the production, research, and trading of Paricalcitol, ensuring that we meet the diverse needs of our clients in the pharmaceutical industry.
02
Physical and chemical properties
Paricalcitol is characterized by its white to off-white crystalline powder. Its molecular weight is 416.65 g/mol and its melting point is about 120-125°C. The compound is soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), but has limited solubility in water. Its stability under various conditions makes it suitable for use in pharmaceutical formulations.
The unique structure of paricalcitol, which contains a hydroxyl group at the 1α position, enhances its potency and selectivity for the vitamin D receptor (VDR). This selectivity is critical to minimizing the side effects common with traditional vitamin D therapy, making paricalcitol the drug of choice for the treatment of secondary hyperparathyroidism.
Paricalcitol is primarily used to treat secondary hyperparathyroidism in patients with chronic kidney disease. Elevated levels of parathyroid hormone can lead to bone disease and cardiovascular complications, so effective management is critical to the health of patients. Paricalcitol works by inhibiting the secretion of parathyroid hormone, thereby helping to maintain normal calcium and phosphorus levels in the blood.
In addition to its primary use, paricalcitol has also been studied for its potential benefits for other diseases, such as osteoporosis and certain types of cancer. Paricalcitol's ability to modulate calcium metabolism and influence cell differentiation has made it an interesting compound for various therapeutic areas.
As a comprehensive enterprise integrating production, R&D and trading, we are committed to providing customers with high-quality Paricalcitol. We adhere to strict quality control measures throughout the production process to ensure that our products meet international standards. Our state-of-the-art facilities are equipped with advanced technology, allowing us to produce Paricalcitol with high purity and consistent quality.
Our dedicated R&D team is constantly exploring new applications and synthesis methods for Paricalcitol, ensuring that we are always at the forefront of innovation in the pharmaceutical industry. With customer satisfaction as our top priority, we provide our customers with comprehensive technical support and logistical assistance to help them navigate the complexities of drug development.
In conclusion, Paricalcitol is an important therapeutic agent for the treatment of secondary hyperparathyroidism and can provide many benefits to patients with chronic kidney disease. With its favorable physical and chemical properties, it effectively maintains calcium and phosphorus balance in the body. Our company's commitment to quality, research, and customer support makes us a reliable partner for businesses seeking high-quality Paricalcitol.
Whether you are involved in drug development or research, our products can help you achieve your goals in the evolving pharmaceutical landscape. To learn more about our Paricalcitol and how it can benefit your project, contact us today!