Oxaliplatin CAS No.61825-94-3 Pharmaceutical Intermediates
introduce
Oxaliplatin belongs to the platinum class anticancer drugs and is widely used to treat various forms of cancer. Its main mechanism of action is to form cross-linking with DNA, hinder DNA replication and transcription, and ultimately trigger cell apoptosis. Unlike cisplatin and carboplatin, oxaliplatin forms larger and more hydrophobic DNA adducts, making it more effective in inhibiting DNA synthesis. In addition, the DACH ligand of oxaliplatin increases the volume and hydrophobicity of the adduct, making it more stable and difficult to repair.
Physical and chemical properties
- Appearance: Oxaliplatin usually appears as a white powder, indicating high purity and quality.
- Solubility: It is soluble in water and organic solvents such as dimethyl sulfoxide (DMSO), which is crucial for its formulation and administration in clinical settings.
- Melting Point: The melting point of oxaliplatin is approximately 200-210°C, which is important for its handling and storage.
- Stability: Oxaliplatin is stable under normal conditions, but should be protected from light and moisture to maintain its efficacy.
- Effective cancer treatment: Oxaliplatin is mainly used to treat colorectal cancer, especially for patients who have not responded to other treatments. It can effectively target cancer cells and is a key drug in oncology.
- Mechanism of action: Oxaliplatin is a platinum compound that works by forming DNA crosslinks, inhibiting DNA replication and transcription, and ultimately leading to cancer cell death. This mechanism is particularly effective against rapidly dividing cells.
- Combination therapy: Oxaliplatin is often used in combination with other chemotherapy drugs, such as fluorouracil and folinic acid, to enhance the therapeutic effect and improve patient prognosis.
- Cost Effective: As a manufacturer and trader, we offer competitive prices without compromising on quality, making it a cost-effective choice for healthcare providers and pharmaceutical companies.
- Custom Synthesis: We offer custom synthesis services to meet specific customer requirements, ensuring our customers receive the exact product required for their application.
- Colorectal cancer treatment: Oxaliplatin is the cornerstone of treatment for metastatic colorectal cancer. It is often included in first-line treatment regimens and has shown significant efficacy in improving patient survival and quality of life.
- Research and Development: In addition to its clinical applications, oxaliplatin is used in research and development. Researchers use this compound to explore new treatment strategies and combinations to enhance its efficacy or reduce side effects.
- Regulatory Compliance: Our manufacturing processes adhere to international quality standards, ensuring our products meet the stringent requirements of the pharmaceutical industry. Commitment to quality and safety is essential to maintaining our reputation as a reliable supplier.
In conclusion, Oxaliplatin is an effective chemotherapy drug that plays a vital role in the treatment of colorectal cancer and other solid tumors. With its unique physical and chemical properties, it can enhance the efficacy of cancer treatment. Our integrated production and trading capabilities enable us to provide high-quality products at competitive prices, backed by our expertise and commitment to customer satisfaction. Whether you are a pharmaceutical manufacturer or a healthcare provider, our Oxaliplatin can meet your needs and contribute to your success in cancer treatment. Contact us today to learn more about our products and services!