Obeticholic Acid CAS No.459789-99-2 Pharmaceutical Intermediates
introduce
Obeticholic acid is a synthetic bile acid derivative that acts as a selective agonist of the farnesoid X receptor (FXR). It is primarily used to treat liver diseases, including primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH). By activating FXR, obeticholic acid plays a key role in regulating bile acid homeostasis, lipid metabolism, and inflammation, making it a promising treatment option for patients with chronic liver disease.
Physical and chemical properties
- Molecular formula: C26H44O4
- Molecular weight: 420.63 g/mol
- Appearance: The compound is usually white powder.
- Appearance: The compound is usually white powder.
- Solubility: Obeticholic acid is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol, and has limited solubility in water, which facilitates various formulation processes.
- Melting Point: The melting point of obeticholic acid is approximately 150-155°C, indicating that it is stable under standard laboratory conditions.
- Chemical Stability: The compound exhibits good stability under recommended storage conditions, ensuring its effectiveness in pharmaceutical formulations.
- Targeted mechanism of action: As a selective FXR agonist, obeticholic acid specifically targets pathways related to liver function, providing a targeted treatment approach.
- Efficacy on liver disease: Clinical studies have demonstrated that the compound is effective in improving liver function and reducing fibrosis in patients with PBC and NASH.
- Quality Assurance: Obeticholic acid is produced under strict quality control measures and complies with international pharmaceutical standards to ensure safety and efficacy.
- Cost Effective: Our integrated manufacturing and trading model enables us to offer competitive prices without compromising quality.
- Global Availability: With a strong distribution network, we ensure timely delivery of obeticholic acid to customers around the world.
Obeticholic acid is an important compound with significant applications in the pharmaceutical industry. Its unique properties, combined with our commitment to quality and reliability, make it an ideal choice for pharmaceutical manufacturers and researchers. By choosing obeticholic acid, you invest in a versatile compound that can drive innovation in liver disease treatment.








