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Methimazole CAS No.60-56-0 Pharmaceutical API
02
introduce
Methimazole is a potent oral antithyroid API and key pharmaceutical intermediate. It selectively inhibits thyroid hormone synthesis, serving as a first-line treatment for hyperthyroidism and Graves disease.
Our products comply with strict international standards to ensure high purity, stable efficacy, and reliable supply for clinical use and pharmaceutical formulation.
02
Physical and chemical properties
Methimazole possesses key physical and chemical characteristics as follows:
- Density: 1.176 (Predicted, 20 °C)
- Melting Point: 144-147 °C
- Boiling Point: 280 °C
- Flash Point: 280 °C
- Storage Temperature: 2-8 °C, sealed, protected from light and moisture
- Solubility: Freely soluble in water (200 g/L); soluble in ethanol and chloroform; slightly soluble in ether and benzene
- Density: 1.176 (Predicted, 20 °C)
- Melting Point: 144-147 °C
- Boiling Point: 280 °C
- Flash Point: 280 °C
- Storage Temperature: 2-8 °C, sealed, protected from light and moisture
- Solubility: Freely soluble in water (200 g/L); soluble in ethanol and chloroform; slightly soluble in ether and benzene
Stronger Efficacy
As an anti-thyroid drug, it is more potent than propylthiouracil. Compared with other similar anti-thyroid drugs, it can inhibit thyroid hormone synthesis more effectively.
As an anti-thyroid drug, it is more potent than propylthiouracil. Compared with other similar anti-thyroid drugs, it can inhibit thyroid hormone synthesis more effectively.
Mild Adverse Reactions
In veterinary clinical practice, compared with propylthiouracil, it has a lower incidence of adverse reactions and better safety, and is the drug of choice for treating feline hyperthyroidism. At the same time, it is a non-hormonal drug, avoiding additional side effects that may be caused by hormonal drugs.
Comprehensive Effect
It can not only directly inhibit the synthesis of thyroid hormones, but also regulate the body's immune function, inhibit the production of abnormal antibodies and restore the normal function of immune cells, it is more comprehensive in the treatment of hyperthyroidism.
Flexible Application
It can be administered orally or made into a transdermal preparation, suitable for animals that cannot tolerate oral administration. Compared with similar drugs that can only be taken orally, it is more flexible to use.
Human Medical Field
It is mainly used to treat hyperthyroidism caused by various reasons, such as Graves' disease and Basedow's disease. It inhibits the peroxidase system in the thyroid gland, hinders the synthesis of thyroxine (T4) and triiodothyronine (T3), and regulates the body's immunity, inhibiting the production of abnormal antibodies and restoring the function of immune cells, thereby reducing the level of thyroid hormones in the body and relieving hyperthyroidism symptoms.
It is mainly used to treat hyperthyroidism caused by various reasons, such as Graves' disease and Basedow's disease. It inhibits the peroxidase system in the thyroid gland, hinders the synthesis of thyroxine (T4) and triiodothyronine (T3), and regulates the body's immunity, inhibiting the production of abnormal antibodies and restoring the function of immune cells, thereby reducing the level of thyroid hormones in the body and relieving hyperthyroidism symptoms.
Veterinary Field
It is the drug of choice for treating feline hyperthyroidism, which can control hyperthyroidism symptoms by inhibiting the synthesis of thyroid hormones in cats; it can also be used to prevent nephrotoxicity caused by cisplatin treatment in dogs, protecting the renal function of dogs.
Chemical and Pharmaceutical Intermediate Field
It can be used as an intermediate for the synthesis of carbimazole to assist drug synthesis; it can also be used as a ligand for antibody purification to help separate and purify antibodies; at the same time, it can be used to prepare nitrile-functionalized room-temperature ionic liquids to assist chemical synthesis experiments.
We implement strict full-process quality control, with each batch of Methimazole undergoing rigorous testing of key indicators including purity, melting point, solubility, stability, and impurity content to meet standards.
Equipped with a stable raw material supply chain and advanced pharmaceutical-grade production facilities, we ensure continuous large-scale supply. Our professional technical team provides tailored services, including formulation optimization, application guidance, and post-sales technical support for clinical and production needs.
Equipped with a stable raw material supply chain and advanced pharmaceutical-grade production facilities, we ensure continuous large-scale supply. Our professional technical team provides tailored services, including formulation optimization, application guidance, and post-sales technical support for clinical and production needs.
As a classic and potent anti-thyroid API, Methimazole plays an irreplaceable role in treating thyroid disorders in humans and animals. With its excellent quality, and reliable supply capacity, we are committed to providing high-quality Methimazole products and professional services for global pharmaceutical companies, clinical institutions, and research laboratories.
Choose our Methimazole to meet your needs in pharmaceutical formulation, clinical treatment, and veterinary medicine. Contact us for more product details and cooperation support.
Choose our Methimazole to meet your needs in pharmaceutical formulation, clinical treatment, and veterinary medicine. Contact us for more product details and cooperation support.