Meldonium CAS No. 76144-81-5 Anti-heart failure drugs
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introduce
Meldonium is a carnitine analog metabolic modulator API that regulates cellular energy metabolism under ischemic and hypoxic conditions. It is widely used for cardioprotection, cerebrovascular disorder management and neuroprotection.
Our strict quality control ensures consistent batch performance for pharmaceutical production needs.
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Physical and chemical properties
Meldonium possesses key physical and chemical characteristics as follows:
- Melting Point: 85-90 °C
- Stability: Hygroscopic
- Solubility: Slightly soluble in water and methanol
- Storage Conditions: Refrigerated storage, keep in dry and sealed containers
Targeted Metabolic Regulation
Inhibits carnitine-dependent fatty acid oxidation, shifts cellular energy substrate to more oxygen-efficient glucose oxidation, optimizes energy utilization under hypoxic/ischemic conditions.
Reliable Cardioprotection
Reduces accumulation of toxic fatty acid metabolic intermediates, stabilizes cell membrane, alleviates myocardial ischemia injury and exerts anti-arrhythmic activity.
Neuroprotective & Cerebroprotective Activity
Optimizes cerebral energy supply, improves blood perfusion in ischemic brain regions, supports functional recovery after cerebrovascular events.
Favorable Safety Profile
Well tolerated with low incidence of mild adverse reactions, suitable for long-term therapeutic use.
Clear Pharmacological Mechanism
Acts as a selective γ-butyrobetaine hydroxylase inhibitor, with well-documented and verified biological activity.
Cardiovascular Therapeutics
Used as core raw material for medications treating stable angina pectoris, chronic heart failure, myocardial infarction recovery and other ischemic heart diseases.
Used as core raw material for medications treating stable angina pectoris, chronic heart failure, myocardial infarction recovery and other ischemic heart diseases.
Neurological & Cerebrovascular Applications
Applied in formulations for acute and chronic cerebral circulation insufficiency, stroke recovery and neurological function improvement.
Adjuvant Therapeutic Uses
Suitable for development of adjuvant therapies for physical/mental fatigue relief, retinal vascular disorder management and alcohol withdrawal syndrome support.
Meldonium is a preferred raw material for the development of cardiovascular and cerebrovascular therapeutic medications, with reliable pharmacological performance and favorable safety profile.
Contact our team today for sample requests, technical specifications and bulk order inquiries—we’re committed to providing efficient and customized pharmaceutical material solutions for you.
Contact our team today for sample requests, technical specifications and bulk order inquiries—we’re committed to providing efficient and customized pharmaceutical material solutions for you.