LCZ696 CAS No.936623-90-4 Pharmaceutical Intermediates

Introducing LCZ696, a breakthrough pharmaceutical compound designed to enhance cardiovascular health. As a product of our state-of-the-art manufacturing facility, LCZ696 combines advanced production technology with stringent quality control to deliver unmatched efficacy and safety. Our company prides itself on integrating manufacturing and trading, ensuring our customers receive not only high-quality products, but also exceptional service. With its unique mechanism of action, LCZ696 stands out in the pharmaceutical industry, offering significant advantages to patients suffering from heart failure and hypertension.

product details

Product details

Product detail

LCZ696, also known as sacubitril/valsartan, is a novel angiotensin receptor neprilysin inhibitor (ARNI) that has been clinically shown to improve outcomes in patients with heart failure with reduced ejection fraction (HFrEF). This innovative compound combines the advantages of neprilysin inhibition and angiotensin receptor blockade, providing a dual mechanism to effectively reduce cardiovascular morbidity and mortality.

product detail

CAS No.	40856-44-8
EINECS	609-874-3
Formula	C9H11NO2
Molecular Weight	165.19
Appearance	White to Off-White solid
Purity	≥98%
Type	Pharmaceutical Intermediates

Physical and Chemical Properties

LCZ696 is a white to light yellow powder that is soluble in organic solvents such as methanol and acetonitrile, with a molecular weight of 847.03 g/mol. Its chemical formula is C48H58N6O8, and it is classified as a complex molecule due to its unique structure that enables it to have dual effects. The stability of LCZ696 under various conditions ensures that it maintains its efficacy throughout its shelf life, making it a reliable choice for pharmaceutical applications.

Advantages

1. Dual mechanism of action: The combination of neprilysin inhibition and angiotensin receptor blockade enables LCZ696 to provide comprehensive cardiovascular protection. This dual action not only lowers blood pressure but also promotes vasodilation, thereby improving cardiac output and reducing the burden on the heart.

2. Improved patient outcomes: Clinical trials have shown that LCZ696 can significantly reduce the risk of cardiovascular death and heart failure hospitalization. Patients treated with LCZ696 have improved quality of life and functional ability, making it the first choice for healthcare providers.

3. Safety: LCZ696 has a favorable safety profile, with side effects that are generally mild and manageable. The careful formulation of the compound minimizes the risk of adverse reactions, ensuring that patients can benefit from its therapeutic effects without experiencing major complications.

4. Multifunctional Applications: Although LCZ696 is primarily used to treat heart failure, its mechanism may also provide potential benefits for the treatment of other cardiovascular diseases, making it a versatile addition to the drug arsenal.

Manufacturing Excellence

As a factory integrating production and trading, our commitment to quality remains unchanged. We adhere to strict Good Manufacturing Practices (GMP) to ensure that each batch of LCZ696 meets the highest standards of purity and potency. Our advanced manufacturing process uses cutting-edge technology and equipment, allowing us to efficiently produce LCZ696 while maintaining strict quality control measures.

Committed to innovation

Our company is committed to ongoing research and development, striving to enhance our product offerings and meet the evolving needs of the pharmaceutical industry. By investing in innovative technologies and establishing partnerships with leading research institutions, our goal is to always be at the forefront of pharmaceutical advancements.

In summary

In summary, LCZ696 represents a significant advancement in the treatment of cardiovascular disease. With its unique dual mechanism of action, proven efficacy, and favorable safety profile, it has the potential to have a lasting impact on patient care. Our commitment to quality manufacturing and innovation ensures that healthcare providers can trust LCZ696 as a reliable option for their patients. Choose LCZ696 for a healthier tomorrow—because every heartbeat counts.