Larotrectinib CAS No.1223403-58-4 Pharmaceutical Intermediates

Introducing Larotrectinib, a breakthrough targeted therapy for the treatment of TRK fusion-positive cancers. This innovative compound is recognized for its high specificity, efficacy, and safety, making it an important addition to the arsenal of drugs to combat various malignancies. As a factory integrating production and trading, we are committed to providing high-quality products at competitive prices, backed by our expertise and dedication to customer satisfaction.

product details

Product details

Product detail

Larotrectinib is a selective inhibitor of tropomyosin receptor kinase (TRK), which is involved in the growth and survival of cancer cells. The compound is particularly effective against tumors that contain TRK gene fusions, which can occur in various types of cancer, including solid tumors in adults and children. By targeting the TRK pathway, larotrectinib can disrupt signals that promote tumor growth, thereby improving patient outcomes.

product detail

CAS No.	40856-44-8
EINECS	609-874-3
Formula	C9H11NO2
Molecular Weight	165.19
Appearance	White to Off-White solid
Purity	≥98%
Type	Pharmaceutical Intermediates

Physical and Chemical Properties

Larotrectinib possesses several key physical and chemical properties that contribute to its effectiveness in pharmaceutical applications:

- Molecular formula: C21H22F2N6O2

- Molecular weight:428.44 g/mol

- Appearance: The compound is typically a yellow powder, indicating high purity and quality.

- Solubility: Larotrectinib is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methanol, facilitating its incorporation into various formulations.

- Stability: The compound exhibits excellent thermal and chemical stability, ensuring its reliability during storage and use.

These properties make larotrectinib a valuable asset to the pharmaceutical industry, where precision and consistency are critical for effective cancer treatment.

Advantages

1. Targeted Therapy: Larotrectinib is specifically designed to target TRK fusions, providing a more effective treatment option for patients with these specific gene mutations. Compared to traditional chemotherapy, this targeted approach minimizes damage to healthy cells, thereby reducing side effects.

2. Highly Effective: Clinical studies have shown that Larotrectinib can lead to significant tumor shrinkage and prolong progression-free survival in patients with TRK fusion-positive cancer, making it a powerful choice in the field of oncology.

3. Broad Applicability: Larotrectinib is effective against a variety of solid tumors, including those of the brain, lung, and other organs, making it a versatile treatment option for oncologists.

4. Cost Effective: By integrating production and trading, we are able to offer competitive prices without compromising quality, providing our customers with excellent value for investment.

5. Expert Support: Our experienced team of professionals is committed to providing excellent customer service and technical support, ensuring our customers have the resources they need to succeed.

Application

Larotrectinib is used extensively in the pharmaceutical industry for a variety of purposes, including:

- Cancer Treatment: Larotrectinib's primary application is in the treatment of TRK fusion-positive cancers, where it has been shown to significantly improve patient outcomes.

- Combination Therapies: Larotrectinib can be used in combination with other therapies to enhance overall treatment and patient outcomes, providing a comprehensive approach to cancer treatment.

- Research: Researchers are using larotrectinib in laboratory studies to explore new approaches and mechanisms of action for cancer treatment and contribute to the advancement of medical science.

In summary

In conclusion, Larotrectinib is a high-quality pharmaceutical compound that offers many advantages for targeted cancer therapy. With its excellent specificity, efficacy, and safety, it is an important component in the fight against TRK fusion-positive cancers. As a factory integrating production and trading, we are committed to providing our customers with the best products and services on the market. Choose Larotrectinib for your drug needs and experience the difference in quality and performance.