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Hyaluronic Acid CAS 9004-61-9 Biomedical & Cosmetic Ingredient
02
introduce
introduce
Hyaluronic Acid (HA) is a natural, non-immunogenic glycosaminoglycan and versatile biomedical & cosmetic ingredient. It features exceptional water-retention capacity, biocompatibility, and viscoelasticity, widely used in cosmetics, pharmaceuticals, and medical devices.
Our products adhere to strict international quality standards, ensuring consistent purity, performance, and supply for diverse application scenarios.
02
Physical and chemical properties
- Density: 1.8±0.1 g/cm3
- LogP: -6.623 (estimated)
- Storage Temperature: -20 °C
- Water-Retention Capacity: Can bind up to 1000x its weight in water
- Viscoelasticity: Forms high-viscosity solutions in water, providing lubricating and protective effects
- Solubility: Soluble in water (5 mg/mL, clear colorless solution); insoluble in ethanol, ether, and other organic solvents
- Stability: Stable under recommended storage conditions; aqueous solutions degrade at pH < 7 or > 7, in presence of hyaluronidase, or under UV/electron beam irradiation
- LogP: -6.623 (estimated)
- Storage Temperature: -20 °C
- Water-Retention Capacity: Can bind up to 1000x its weight in water
- Viscoelasticity: Forms high-viscosity solutions in water, providing lubricating and protective effects
- Solubility: Soluble in water (5 mg/mL, clear colorless solution); insoluble in ethanol, ether, and other organic solvents
- Stability: Stable under recommended storage conditions; aqueous solutions degrade at pH < 7 or > 7, in presence of hyaluronidase, or under UV/electron beam irradiation
1. Unsurpassed Natural Moisturizing Ability
It is the most effective natural moisturizing substance found in nature, with far better water retention and locking effects than ordinary moisturizers. It forms a three-dimensional hydration network to firmly lock in water, and is water-soluble and grease-free in itself. When used as a moisturizing ingredient, it can greatly reduce the addition of lubricants and emollients in the formula.
2. Excellent Biocompatibility
Naturally present in human tissues such as the skin, joints and eyes, it is non-immunogenic and non-adhesive, with high affinity for human tissues. No rejection, allergy or other adverse reactions are likely to occur for external or medical use, an advantage that synthetic moisturizers and some medical auxiliary materials cannot match.
3. Diversified Functions and Strong Adaptability
It has multiple functions such as moisturizing, lubrication, tissue repair and morphological support. Hyaluronic acid with different molecular weights can exert targeted effects, and has a wider range of applicable scenarios compared with skin care or medical materials with a single function. It can also synergize with other ingredients, and can help the skin absorption of other active ingredients when used as a skin care base.
4. Outstanding Medical Auxiliary Effect
It has good viscoelasticity and physicochemical stability. It can effectively maintain the spatial shape of tissues and provide a clear operating field of vision in surgery, while protecting surrounding tissues and reducing postoperative inflammation and complications. Compared with ordinary surgical auxiliary materials, it has a better effect on protecting human tissues and assisting postoperative recovery.
It is the most effective natural moisturizing substance found in nature, with far better water retention and locking effects than ordinary moisturizers. It forms a three-dimensional hydration network to firmly lock in water, and is water-soluble and grease-free in itself. When used as a moisturizing ingredient, it can greatly reduce the addition of lubricants and emollients in the formula.
2. Excellent Biocompatibility
Naturally present in human tissues such as the skin, joints and eyes, it is non-immunogenic and non-adhesive, with high affinity for human tissues. No rejection, allergy or other adverse reactions are likely to occur for external or medical use, an advantage that synthetic moisturizers and some medical auxiliary materials cannot match.
3. Diversified Functions and Strong Adaptability
It has multiple functions such as moisturizing, lubrication, tissue repair and morphological support. Hyaluronic acid with different molecular weights can exert targeted effects, and has a wider range of applicable scenarios compared with skin care or medical materials with a single function. It can also synergize with other ingredients, and can help the skin absorption of other active ingredients when used as a skin care base.
1. Cosmetics and Skin Care Field
As a core moisturizing ingredient, it is added to various high-end cosmetics such as creams, lotions, masks, serums and eye drops. It can improve skin water content and elasticity, refine rough skin texture, and act as a moisturizing base to enhance the absorption of other skin care ingredients.
2. Medical Clinical Field
(1) Core ophthalmic medicine: An essential drug for ophthalmic "viscous surgery", widely used in cataract, intraocular lens implantation, corneal transplantation, glaucoma filtration, retinal detachment and other ophthalmic surgeries. It can protect intraocular tissues, maintain a clear surgical field of vision, and reduce the incidence of postoperative inflammation and complications.
(2) Surgical/orthopaedic adjuvant: Low molecular weight hyaluronic acid can be used as a surgical lubricant for joint surgeries such as knee joint surgery to play a joint lubrication role. It can also regulate vascular permeability, promote collagen deposition and assist in the wound healing of various injuries.
(3) Skin tissue care: It can be used for the repair and shaping of skin tissue by injection, and the injection formulation has a much slower metabolic rate than the external formulation, which can maintain a longer-lasting effect.
3. Veterinary Field
Used as a therapeutic agent for animal synovitis, and also as an adjuvant for animal ophthalmic surgery to exert the effects of viscoelastic support and protection of intraocular tissues.
As a core moisturizing ingredient, it is added to various high-end cosmetics such as creams, lotions, masks, serums and eye drops. It can improve skin water content and elasticity, refine rough skin texture, and act as a moisturizing base to enhance the absorption of other skin care ingredients.
2. Medical Clinical Field
(1) Core ophthalmic medicine: An essential drug for ophthalmic "viscous surgery", widely used in cataract, intraocular lens implantation, corneal transplantation, glaucoma filtration, retinal detachment and other ophthalmic surgeries. It can protect intraocular tissues, maintain a clear surgical field of vision, and reduce the incidence of postoperative inflammation and complications.
(2) Surgical/orthopaedic adjuvant: Low molecular weight hyaluronic acid can be used as a surgical lubricant for joint surgeries such as knee joint surgery to play a joint lubrication role. It can also regulate vascular permeability, promote collagen deposition and assist in the wound healing of various injuries.
(3) Skin tissue care: It can be used for the repair and shaping of skin tissue by injection, and the injection formulation has a much slower metabolic rate than the external formulation, which can maintain a longer-lasting effect.
3. Veterinary Field
Used as a therapeutic agent for animal synovitis, and also as an adjuvant for animal ophthalmic surgery to exert the effects of viscoelastic support and protection of intraocular tissues.
We implement strict full-process quality control, with each batch of Hyaluronic Acid undergoing rigorous testing of key indicators including purity, molecular weight distribution, viscoelasticity, water content, and biocompatibility to meet international standards.
Equipped with a stable raw material supply chain (bacterial fermentation or animal tissue-derived, traceable sources), we ensure continuous large-scale supply. Our professional technical team provides tailored services, including formulation optimization, application guidance, and molecular weight grade selection support.
Equipped with a stable raw material supply chain (bacterial fermentation or animal tissue-derived, traceable sources), we ensure continuous large-scale supply. Our professional technical team provides tailored services, including formulation optimization, application guidance, and molecular weight grade selection support.
As a classic natural glycosaminoglycan, Hyaluronic Acid plays an irreplaceable role in cosmetics, biomedicine, and veterinary care due to its unique moisturizing, lubricating, and biocompatible properties. With stable product quality, diversified application scenarios, and reliable supply capacity, we are committed to providing high-quality Hyaluronic Acid and professional services for global customers.
Choose our Hyaluronic Acid to meet your needs in cosmetic formulation, medical device production, and pharmaceutical development. Contact us for more product details and cooperation support.
Choose our Hyaluronic Acid to meet your needs in cosmetic formulation, medical device production, and pharmaceutical development. Contact us for more product details and cooperation support.


