Florfenicol CAS No. 73231-34-2 (GMP/DMF) Veterinary Antibacterial API
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introduce
Florfenicol is exclusive veterinary broad-spectrum bacteriostatic API. It inhibits bacterial protein synthesis, effective against Gram-positive, Gram-negative bacteria and mycoplasma, widely used for livestock, poultry and aquaculture bacterial infection formulations.
Strict GMP production and full batch HPLC testing guarantee stable purity for veterinary drug manufacturers.
Strict GMP production and full batch HPLC testing guarantee stable purity for veterinary drug manufacturers.
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Physical and chemical properties
Florfenicol possesses key physical and chemical characteristics as follows:
- Predicted Density: 1.45±0.1 g/cm³
- Melting Point: 153 °C
- Boiling Point: 618 °C
- Storage Condition: 2–8 °C, sealed light-proof dry container, avoid strong oxidants
- Solubility: Freely soluble in DMF; soluble in methanol and ethanol; slightly soluble in glacial acetic acid; practically insoluble in water and chloroform
- Stability: Stable under sealed low-temperature storage, slight light discoloration after long exposure
- Predicted Density: 1.45±0.1 g/cm³
- Melting Point: 153 °C
- Boiling Point: 618 °C
- Storage Condition: 2–8 °C, sealed light-proof dry container, avoid strong oxidants
- Solubility: Freely soluble in DMF; soluble in methanol and ethanol; slightly soluble in glacial acetic acid; practically insoluble in water and chloroform
- Stability: Stable under sealed low-temperature storage, slight light discoloration after long exposure
Superior Antibacterial Potency
Antibacterial activity 15–20 times stronger than chloramphenicol and thiamphenicol, low MIC value against susceptible strains.
Antibacterial activity 15–20 times stronger than chloramphenicol and thiamphenicol, low MIC value against susceptible strains.
Low Drug Resistance Risk
Fluorinated molecular structure overcomes chloramphenicol/ thiamphenicol resistance; resistant bacteria to quinolones, penicillins still sensitive to florfenicol.
High Animal Safety
No aplastic anemia risk, the core toxic nitrobenzene group of chloramphenicol is removed from molecular structure.
Rapid Absorption & Wide Tissue Distribution
Peak tissue concentration within 60 min after oral administration, long elimination half-life for long-acting treatment.
Wide Formulation Compatibility
Adaptable to premix, soluble powder, injection and oral liquid production.
Low Medication Cost
More cost-effective than macrolide veterinary antibiotics for mass livestock and poultry farm prevention & treatment programs.
Florfenicol is a broad-spectrum antibiotic, widely used for the prevention and treatment of various bacterial diseases of livestock, poultry and aquaculture caused by susceptible bacteria.
Livestock
For pigs: Treat swine pleuropneumonia, enzootic pneumonia, streptococcosis, colibacillosis, salmonellosis, piglet yellow-white scour, atrophic rhinitis, respiratory infections, pasteurellosis, and swine respiratory disease complex (SRDC).
For cows: Cure bovine respiratory disease and foot rot caused by Pasteurella and Fusobacterium, combat mastitis, respiratory infections, and bacterial infections associated with foot rot.
For sheep: Address respiratory infections and bacterial infections linked to foot rot.
For cows: Cure bovine respiratory disease and foot rot caused by Pasteurella and Fusobacterium, combat mastitis, respiratory infections, and bacterial infections associated with foot rot.
For sheep: Address respiratory infections and bacterial infections linked to foot rot.
Poultry
For chickens: Control chronic respiratory disease, infectious rhinitis, colibacillosis, salmonellosis, and respiratory infections caused by pathogens such as Pasteurella multocida or Mycoplasma gallisepticum.
For ducks and geese: Control colibacillosis, salmonellosis and mixed bacterial infections.
For ducks and geese: Control colibacillosis, salmonellosis and mixed bacterial infections.
Aquaculture
For fish: Treat vibriosis, enteritis, ascites, tilapia francisellosis, bacterial gill infections and Enteric Redmouth Disease (ERM).
For shrimp: Combat Necrotizing Hepatopancreatitis (NHP).
For crabs: Cure rotten gill, red leg disease and control bacterial infections.
For turtles: Cure turtle furunculosis.
For sea cucumbers: Address bacterial issues and promote overall health.
For shrimp: Combat Necrotizing Hepatopancreatitis (NHP).
For crabs: Cure rotten gill, red leg disease and control bacterial infections.
For turtles: Cure turtle furunculosis.
For sea cucumbers: Address bacterial issues and promote overall health.
Laboratory Reference Standard
It can be used as HPLC analytical standard for veterinary drug residue detection and amphenicol antibacterial mechanism research.
Florfenicol is the mainstream broad-spectrum veterinary amphenicol API with verified safety and strong antibacterial efficacy. It solves the aplastic anemia hidden danger of chloramphenicol and shows low cross-resistance, covering livestock, poultry and aquaculture infection treatment scenarios with stable long-term market demand.
Contact our team today for sample requests, technical specifications and bulk order inquiries—we’re committed to providing efficient and customized veterinary raw material solutions for you.
Contact our team today for sample requests, technical specifications and bulk order inquiries—we’re committed to providing efficient and customized veterinary raw material solutions for you.