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    Dactolisib CAS No. 915019-65-7 Pharmaceutical Intermediates

    Product name

    Dactolisib

    CAS No. 

    915019-65-7

    EINECS  

    1312995-182-4

    Formula 

    C30H23N5O

    Molecular Weight

    469.55

    Appearance

    white to off-white crystalline powder

    Purity

    ≥98%

    Type

    Pharmaceutical Intermediates

    - High Potency: Dactolisib is a potent dual inhibitor of the phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) pathways, making it a valuable candidate for cancer treatment.

    - Broad Spectrum of Activity: Effective against various cancer types, including breast, lung, and prostate cancers, providing a versatile option for oncological research.

    - Excellent Safety Profile: Demonstrates a favorable safety and tolerability profile in clinical studies, allowing for potential long-term use in patients.

    - Reliable Supplier: As a leading foreign trade company, we ensure timely delivery and exceptional customer service.

    - Comprehensive Technical Support: We provide extensive documentation and technical assistance to facilitate your research and development efforts.

      Product details

      ATALUREN 775304-57-9 (1)
      02

      introduce

      Dactolisib, also known as BEZ235, is an investigational drug that acts as a dual inhibitor of the PI3K and mTOR signaling pathways, which are critical for cell growth, proliferation, and survival. By inhibiting these pathways, Dactolisib has shown promise in preclinical and clinical studies for its ability to suppress tumor growth and enhance the efficacy of other anticancer therapies. Its unique mechanism of action makes it a valuable tool in the fight against various malignancies.
      5434-20-8 (3)
      02

      Physical and chemical properties

      Dactolisib possesses several important physical and chemical properties that contribute to its effectiveness and utility in various applications:

      - Molecular Formula: C30H23N5O
      - Molecular Weight:469.55 g/mol
      - Appearance: white to off-white crystalline powder.
      - Melting Point: The compound has a melting point in the range of 150-160 °C, indicating good thermal stability.
      - Solubility: Dactolisib is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methanol, but has limited solubility in water. This solubility profile is advantageous for various formulation processes.
      - Stability: Exhibits stability under standard laboratory conditions, making it suitable for long-term storage and use in synthesis.

      advantage

      The advantages of using Dactolisib in your research and development projects are significant:

      1. Dual Inhibition: By targeting both the PI3K and mTOR pathways, Dactolisib offers a synergistic approach to cancer treatment, potentially overcoming resistance mechanisms seen with single-agent therapies.
      2. Broad Antitumor Activity: Dactolisib has demonstrated efficacy against a wide range of cancer types, making it a versatile candidate for combination therapies and personalized medicine approaches.
      3. Quality Assurance: Our product is manufactured under strict quality control measures, ensuring consistency and reliability for your research and production needs.
      4. Research Applications: Frequently utilized in cancer research, Dactolisib is ideal for developing new therapeutic strategies and understanding the underlying mechanisms of tumor biology.

      Laboratory Instrumentation and Consumables

      As a foreign trade company, we recognize the importance of having the right tools and consumables for your laboratory needs. Dactolisib is compatible with various laboratory instrumentation, including:

      - High-Performance Liquid Chromatography (HPLC): Essential for analyzing the purity and concentration of the compound in solution.
      - Nuclear Magnetic Resonance (NMR) Spectroscopy: Useful for determining the molecular structure and dynamics of the compound.
      - Mass Spectrometry (MS): Critical for identifying and quantifying chemical compounds in complex mixtures.
      - Infrared (IR) Spectroscopy: Helps in characterizing functional groups and confirming the presence of specific moieties.

      In addition to our high-quality Dactolisib, we offer a range of laboratory consumables, including glassware, reagents, and safety equipment, to ensure that your research and development processes run smoothly.

      Conclusion

      Dactolisib is a highly valuable compound for various applications in cancer research and therapy. With its excellent physical and chemical properties, it serves as a crucial tool for understanding and targeting the PI3K/mTOR signaling pathways in cancer cells. As a reliable foreign trade company, we are committed to providing high-quality products and exceptional customer service to meet your laboratory needs. Contact us today to learn more about our offerings and how we can support your research and development efforts.