Ciprofloxacin HCL CAS No. 86393-32-0 (GMP/DMF) Antibacterial API
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introduce
Ciprofloxacin Hydrochloride Hydrate is a second-generation fluoroquinolone antibacterial API that exerts bactericidal effects by inhibiting bacterial DNA gyrase. It is widely used for treating bacterial infections in the urinary, respiratory and gastrointestinal systems.
Our strict quality control ensures consistent batch performance for pharmaceutical production needs.
Our strict quality control ensures consistent batch performance for pharmaceutical production needs.
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Physical and chemical properties
Ciprofloxacin Hydrochloride Hydrate possesses key physical and chemical characteristics as follows:
- Melting Point: 318-320 °C
- pH Value: 3.0–4.5
- Solubility: Soluble in water; slightly soluble in methanol; very slightly soluble in anhydrous ethanol; practically insoluble in acetone, ethyl acetate and methylene chloride
- Storage Conditions: Store in sealed, dry containers at low temperature, protected from light and moisture
- Melting Point: 318-320 °C
- pH Value: 3.0–4.5
- Solubility: Soluble in water; slightly soluble in methanol; very slightly soluble in anhydrous ethanol; practically insoluble in acetone, ethyl acetate and methylene chloride
- Storage Conditions: Store in sealed, dry containers at low temperature, protected from light and moisture
Broad-spectrum Bactericidal Activity
Potent activity against Enterobacteriaceae (E. coli, Klebsiella) and Pseudomonas aeruginosa, with superior efficacy to older fluoroquinolones against Gram-positive pathogens.
Potent activity against Enterobacteriaceae (E. coli, Klebsiella) and Pseudomonas aeruginosa, with superior efficacy to older fluoroquinolones against Gram-positive pathogens.
Clear Mechanism
Selectively inhibits bacterial DNA gyrase, blocks DNA synthesis and replication, leading to rapid bacterial death.
Good Formulation Adaptability
Favorable water solubility supports development of tablets, injections, topical solutions and other dosage forms.
High Bioavailability
Rapidly absorbed after oral administration, widely distributed across tissues and body fluids.
Proven Clinical Efficacy
Well-established safety and therapeutic profile, widely adopted in global clinical anti-infection practice.
Systemic Infection Treatment
Core raw material for medications targeting urinary tract, respiratory tract and gastrointestinal bacterial infections, as well as gonorrhea and septicemia caused by susceptible strains.
Core raw material for medications targeting urinary tract, respiratory tract and gastrointestinal bacterial infections, as well as gonorrhea and septicemia caused by susceptible strains.
Topical & Otological Use
Applied in otic preparations for otitis media, external otitis and myringitis, as well as ophthalmic and topical antibacterial formulations.
Ciprofloxacin Hydrochloride Hydrate is a clinically validated broad-spectrum fluoroquinolone antibacterial API with reliable efficacy and high formulation flexibility.
Contact our team today for sample requests, technical specifications and bulk order inquiries—we’re committed to providing efficient and customized pharmaceutical material solutions for you.
Contact our team today for sample requests, technical specifications and bulk order inquiries—we’re committed to providing efficient and customized pharmaceutical material solutions for you.