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0102030405

404844-02-6 N-DESMETHYL IMATINIB 结构式.png

EZETIMIBE 163222-33-1 INTERMEDIATES外包装.png

CAS No 404844-02-6 N-DESMETHYL IMATINIB Pharmaceutical Intermediates

Product name	N-DESMETHYL IMATINIB
CAS No.	404844-02-6
EINECS	1592732-453-0
Formula	C28H29N7O
Molecular Weight	479.58
Appearance	Light yellow to yellow lyophilized solid
Purity	≥98%
Type	Pharmaceutical Intermediates

Active metabolite of imatinib: N-desmethylimatinib is the active metabolite of imatinib, a well-known tyrosine kinase inhibitor used For the treatment of various cancers, especially chronic myelogenous leukemia (CML) and gastrointestinal stromal tumors (GIST).

HIGH PURITY & QUALITY: Produced in our state-of-the-art facility ensuring compliance with the highest pharmaceutical standards.

Integrated Production and Trading: As an integrated production and trading factory, we provide competitive prices and reliable supply chain solutions.

Regulatory Compliance: Our products comply with all necessary regulatory requirements to ensure safety and effectiveness in pharmaceutical applications.

Research-Supported Efficacy: N-desmethylimatinib has demonstrated significant therapeutic potential in oncology, supported by extensive research.

product details

Product details

Product detail

N-desmethylimatinib is a key compound in the pharmaceutical industry, especially oncology. As the major active metabolite of imatinib, it retains the therapeutic properties of imatinib in inhibiting the BCR-ABL tyrosine kinase, which is responsible for chronic myelogenous leukemia and gastrointestinal stromal tumors. The main culprit of cancer cell proliferation. The compound's ability to selectively target cancer cells while sparing normal cells makes it valuable in cancer treatment regimens.

product detail

CAS No.	40856-44-8
EINECS	609-874-3
Formula	C9H11NO2
Molecular Weight	165.19
Appearance	White to Off-White solid
Purity	≥98%
Type	Pharmaceutical Intermediates

Advantages

The advantages of N-desmethylimatinib are not limited to its chemical composition. Here are some of the key benefits that make it the first choice in the pharmaceutical industry:

1. Targeted cancer therapy: N-desmethylimatinib effectively inhibits BCR-ABL tyrosine kinase and provides targeted therapy for CML and GIST patients, thereby improving treatment effects.

2. Enhanced Efficacy: As the active metabolite of imatinib, N-desmethylimatinib has been shown to maintain therapeutic efficacy, making it a key component in cancer treatment regimens.

3. Improved Bioavailability: The chemical properties of the compound contribute to its absorption and bioavailability, ensuring optimal therapeutic results for patients.

4. Research-Driven Development: Supported by extensive clinical studies, N-desmethylimatinib has shown promise across multiple therapeutic areas, making it a valuable addition to any oncology portfolio.

5. Comprehensive Support: Our integrated factory model ensures that we not only provide products, but also provide comprehensive support, including technical assistance and regulatory guidance.

Physical and chemical properties

N-desmethylimatinib has unique physical and chemical properties that contribute to its effectiveness as a drug.

- Molecular formula: C28H29N7O

- Molecular Weight: 479.58g/mol

- Appearance: Light yellow to yellow lyophilized solid

- Solubility: Soluble in dimethyl sulfoxide (DMSO) and methanol; slightly soluble in water

- Melting point: approx. 150-155 °C

- STABILITY: Stable under normal storage conditions with recommended shelf life ensuring long-term efficacy.

These properties not only enhance the compound's performance but also facilitate its formulation into a variety of pharmaceutical products, including tablets and injections.

Committed to quality and compliance

As a factory integrating production and trading, we pride ourselves on our commitment to quality and compliance. Our manufacturing processes follow Good Manufacturing Practices (GMP), ensuring that each batch of N-desmethylimatinib meets strict quality standards. From raw materials to finished products, we conduct rigorous testing at every stage of production to ensure safety and effectiveness.

Our factory is equipped with advanced technology and staffed by a team of experienced professionals dedicated to maintaining the highest level of quality control. We understand the critical nature of pharmaceutical products and are committed to providing the best products to our customers.

In summary

In summary, N-desmethylimatinib represents a major advance in targeted cancer therapy. Its unique physical and chemical properties, proven efficacy and our commitment to quality make it a leading choice in the pharmaceutical industry. As an integrated manufacturing and trading facility, we are well-positioned to meet the growing demand for this essential compound, ensuring healthcare providers and patients have access to the best treatment options. Choose N-desmethylimatinib for a reliable, effective oncology solution.