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    CAS NO 1350653-20-1 Vericiguat Pharmaceutical Intermediates

    Product name

    Vericiguat

    CAS No.

    1350653-20-1

    EINECS  

    /

    Formula

    C19H16F2N8O2

    Molecular Weight

    426.38

    Appearance

    Light yellow to brown Powder

    Purity

    ≥98%

    Type

    Pharmaceutical Intermediates

     High Purity: Our Vericiguat is manufactured to the highest purity standards, ensuring reliable performance in pharmaceutical applications.

    Targeted Action: This compound is specifically designed to treat heart failure with reduced ejection fraction, providing effective relief to patients.

     Integrated Production and Trading: As a production and trading integrated factory, we provide competitive prices and a stable supply of high-quality chemicals.

     Expertise and Experience: With many years of experience in chemical manufacturing, we guarantee that our products meet the highest industry standards.

    Custom Solutions: We offer custom solutions to meet specific customer requirements, including custom synthesis and packaging options.

      Product details

      CAS No
      02

      Product detail

        Vericiguat is a novel oral soluble guanylate cyclase (sGC) stimulator that plays an important role in the treatment of heart failure with reduced ejection fraction (HFrEF). By enhancing the sensitivity of sGC to nitric oxide, Vericiguat increases intracellular cyclic guanosine monophosphate (cGMP) levels, leading to vasodilation and improved cardiac function. This innovative mechanism of action makes Vericiguat a valuable addition to existing treatment options for the treatment of heart failure, especially for patients with recent worsening of heart failure.

      138982-67-9 ZIPRASIDONE HYDROCHLORIDE 外包装3
      02

      product detail

      CAS No.

      40856-44-8

      EINECS 

      609-874-3

      Formula

      C9H11NO2

      Molecular Weight

      165.19

      Appearance

      White to Off-White solid

      Purity

      98%

      Type

      Pharmaceutical Intermediates

      Advantages 

       1. Effective treatment of heart failure: Vericiguat provides a targeted approach to treat heart failure with reduced ejection fraction, bringing significant symptom relief and improving overall quality of life to patients.
       2. Minimal Side Effects: Vericiguat has fewer side effects than traditional heart failure drugs, making it a suitable option for patients who may be adversely affected by other treatments.
       3. Customizable Formulation: Our integrated plant capabilities enable us to offer customizable formulations, enabling customers to develop specific dosage forms suitable for their target patient population.
       4. Regulatory Compliance: We adhere to strict regulatory standards to ensure our products meet international quality and safety regulations and are suitable for pharmaceutical applications.
       5. Reliable supply chain: As a production and trading integrated factory, we maintain a strong supply chain to ensure timely delivery and continuous supply of products.

       Application

       Vericiguat is used primarily in the pharmaceutical industry for the treatment of heart failure with reduced ejection fraction. Its unique mechanism of action enables it to effectively manage symptoms associated with this condition, including:
       - Improved cardiac output: Increases the heart's ability to pump blood efficiently and reduces symptoms of heart failure.
       - Vasodilation: Promotes relaxation of blood vessels, helping to lower blood pressure and reduce the heart's workload.
       - Relieve symptoms: Relieve symptoms such as shortness of breath and fatigue, and improve patients' quality of life.

      Physical and chemical properties

      - Molecular formula: C22H30N4O4S
      - Molecular weight: 446.56 g/mol
      - Appearance: White to off-white crystalline powder
      - Solubility: Soluble in dimethyl sulfoxide (DMSO) and methanol; slightly soluble in water.
      - Melting point: approx. 150-155°C
      - Stability: Vericiguat is stable under normal storage conditions, keep in a cool and dry place away from direct sunlight, with a recommended shelf life of two years.
       Vericiguat's physical and chemical properties make it an ideal candidate for various applications in drug formulation and development. Its solubility properties allow for easy incorporation into different dosage forms, thereby improving bioavailability and therapeutic efficacy. The compound's stability ensures that it maintains its effectiveness throughout its shelf life, making it a reliable choice for pharmaceutical manufacturers.

      In summary

        In summary, Vericiguat is a high-quality pharmaceutical compound with great potential in the treatment of heart failure with reduced ejection fraction. With our commitment to quality, expertise and customer satisfaction, we are a trusted partner for all your pharmaceutical needs. Contact us today to learn more about our products and how we can support your drug development projects. Our commitment to innovation and excellence ensures that you receive the best possible product tailored to your specific requirements.