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0102030405

CAS NO 1257044-40-8 Venetoclax Pharmaceutical Intermediates

Product name	Venetoclax
CAS No.	1257044-40-8
EINECS	820-130-9
Formula	C45H50ClN7O7S
Molecular Weight	868.44
Appearance	Light Yellow to Yellow Powder
Purity	≥98%
Type	Pharmaceutical Intermediates

High Purity: Our Venetoclax is manufactured to the highest purity standards, ensuring reliable performance in pharmaceutical applications.

Targeted Action: This compound is specifically designed to inhibit B-cell lymphoma 2 (BCL-2), providing effective treatment for certain types of blood cancers.

Integrated Production and Trade: As a production and trade integrated factory, we offer competitive pricing and a consistent supply of high-quality chemicals.

Expertise and Experience: With years of experience in chemical manufacturing, we guarantee that our products meet the highest industry standards.

Custom Solutions: We provide tailored solutions to meet specific customer requirements, including custom synthesis and packaging options.

product details

Product details

Product detail

Venetoclax is a potent and selective BCL-2 inhibitor that plays a significant role in the treatment of hematological malignancies, particularly chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML). By selectively binding to the BCL-2 protein, Venetoclax promotes apoptosis (programmed cell death) in cancer cells, leading to reduced tumor burden and improved patient outcomes. This innovative mechanism of action makes Venetoclax a valuable addition to the therapeutic arsenal for managing blood cancers.

138982-67-9 ZIPRASIDONE HYDROCHLORIDE 外包装3

product detail

CAS No.	40856-44-8
EINECS	609-874-3
Formula	C9H11NO2
Molecular Weight	165.19
Appearance	White to Off-White solid
Purity	≥98%
Type	Pharmaceutical Intermediates

Physical and Chemical Properties

- Molecular Formula: C28H31ClN6O4S

- Molecular Weight: 868.10 g/mol

- Appearance: White to off-white crystalline powder

- Solubility: Soluble in dimethyl sulfoxide (DMSO) and methanol; slightly soluble in water.

- Melting Point: Approximately 150-155°C

- Stability: Venetoclax is stable under normal storage conditions, with a recommended shelf life of two years when kept in a cool, dry place away from direct sunlight.

The physical and chemical properties of Venetoclax make it an ideal candidate for various applications in drug formulation and development. Its solubility profile allows for easy incorporation into different dosage forms, enhancing bioavailability and therapeutic efficacy. The compound's stability ensures that it maintains its effectiveness throughout its shelf life, making it a reliable choice for pharmaceutical manufacturers.

Advantages

1. Effective Treatment for Blood Cancers: Venetoclax provides a targeted approach to managing chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML), offering patients significant relief from symptoms and improving overall quality of life.

2. Minimal Side Effects: Compared to traditional chemotherapy, Venetoclax has a favorable side effect profile, making it a suitable option for patients who may experience adverse effects from other treatments.

3. Customizable Formulations: Our integrated factory capabilities enable us to offer customizable formulations, allowing clients to develop specific dosage forms tailored to their target patient populations.

4. Regulatory Compliance: We adhere to strict regulatory standards, ensuring that our products are compliant with international quality and safety regulations, making them suitable for pharmaceutical applications.

5. Reliable Supply Chain: As a production and trade integrated factory, we maintain a robust supply chain, ensuring timely delivery and consistent availability of our products.

Application

Venetoclax is primarily used in the pharmaceutical industry for the treatment of hematological malignancies. Its unique mechanism of action allows it to effectively manage the symptoms associated with these conditions, including:

- Chronic Lymphocytic Leukemia (CLL): Venetoclax is indicated for the treatment of CLL, particularly in patients with 17p deletion or those who have received prior therapy.

- Acute Myeloid Leukemia (AML): Research is ongoing into the efficacy of Venetoclax in combination with other agents for the treatment of AML.

- Combination Therapy: Venetoclax is often used in combination with other therapies to enhance treatment efficacy and improve patient outcomes.

In summary

In conclusion, Venetoclax is a high-quality pharmaceutical compound with significant potential in the treatment of blood cancers. With our commitment to quality, expertise, and customer satisfaction, we are your trusted partner for all your pharmaceutical needs. Contact us today to learn more about our products and how we can support your pharmaceutical development projects. Our dedication to innovation and excellence ensures that you receive the best products tailored to your specific requirements.