Canagliflozin CAS No.842133-18-0 Pharmaceutical Intermediates
overview
Canagliflozin is a highly effective sodium-glucose co-transporter 2 (SGLT2) inhibitor used primarily for the management of type 2 diabetes mellitus.
By inhibiting the SGLT2 protein in the kidneys, Canagliflozin reduces glucose reabsorption, leading to increased glucose excretion in urine and consequently lowering blood sugar levels.
Our Canagliflozin is produced under stringent quality control measures, ensuring that it meets the highest standards for purity and efficacy.
Physical and Chemical Properties
- Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methanol but has limited solubility in water.
- Melting Point: approximately 150-155°C.
- Stability: Stable under proper storage conditions.
The chemical structure of Canagliflozin features a unique combination of a chlorobenzene ring and a sulfonamide group, which are essential for its biological activity.
This structure allows Canagliflozin to effectively bind to the SGLT2 protein, inhibiting its function and promoting glucose excretion.
1. Effective Glycemic Control: Canagliflozin has been shown to significantly lower HbA1c levels, making it an effective option for managing blood sugar in type 2 diabetes patients.
2. Weight Management: Patients using Canagliflozin often experience weight loss, which can be beneficial for those with type 2 diabetes who are overweight or obese.
3. Cardiovascular Benefits: Clinical studies suggest that Canagliflozin may reduce the risk of cardiovascular events in patients with type 2 diabetes, providing additional health benefits.
4. Renal Protection: Canagliflozin has been shown to have protective effects on kidney function, making it a valuable option for patients with diabetic kidney disease.
To ensure optimal results in your research and applications involving Canagliflozin, we offer a range of laboratory equipment and supplies, including:
- High-Performance Liquid Chromatography (HPLC) Systems: Essential for the analysis and quantification of Canagliflozin in various formulations.
- Mass Spectrometers: For precise identification and quantification of Canagliflozin and its metabolites.
- Reagents and Standards: High-quality reagents and calibration standards to ensure accurate and reliable results in your experiments.
- Storage Solutions: Specialized containers and conditions to maintain the stability and integrity of Canagliflozin.
Canagliflozin is an essential medication for the effective management of type 2 diabetes, offering numerous health benefits. With our high-quality Canagliflozin and comprehensive support, you can trust us to meet your needs effectively.
As a leading foreign trade company, we are committed to providing high-quality products and exceptional customer service. Our Canagliflozin is sourced from reputable manufacturers and undergoes rigorous testing to ensure compliance with international standards. We understand the importance of reliable supply chains and offer flexible ordering options to accommodate your specific needs.
Our dedicated team of experts is always available to provide technical support and guidance, ensuring that you can make the most of our products. Whether you are in the pharmaceutical industry, academic research, or any other field requiring high-quality Canagliflozin, we are here to support your success.
Contact us today to learn more about our products and how we can assist you in achieving your health and research goals.