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    CABOZANTINIB (S)-MALATE CAS No. 1140909-48-3 Pharmaceutical Intermediates

    Product name

    CABOZANTINIB (S)-MALATE

    CAS No. 

    1140909-48-3

    EINECS  

    691-711-0

    Formula 

    C32H30FN3O10

    Molecular Weight

    635.6

    Appearance

    white to off-white crystalline powder

    Purity

    ≥98%

    Type

    Pharmaceutical Intermediates

    - High Purity: Our Cabozantinib (S)-Malate is manufactured to meet the highest purity standards, ensuring optimal efficacy in pharmaceutical applications.

    - Targeted Therapy: This compound is recognized for its role as a potent inhibitor of multiple receptor tyrosine kinases, making it a valuable asset in cancer treatment.

    - Versatile Applications: Suitable for research and development in oncology, particularly in studies related to renal cell carcinoma and other solid tumors.

    - Reliable Supplier: As a trusted foreign trade company, we ensure timely delivery and consistent quality, supported by rigorous quality control processes.

    - Comprehensive Support: We provide extensive technical documentation and customer support to assist clients in utilizing our products effectively.

      Product details

      1140909-48-3 (1)
      02

      overview

      Cabozantinib (S)-Malate is a small molecule drug that acts as a multi-kinase inhibitor, primarily targeting the MET, VEGFR2, and RET pathways. It is a malate salt of Cabozantinib, which enhances its solubility and bioavailability.

      This compound is primarily used in the treatment of various cancers, including advanced renal cell carcinoma and hepatocellular carcinoma.
      CAS NO
      02

      Physical and chemical properties

      - Solubility: It is highly soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methanol, while showing limited solubility in water.
      - Melting Point: The melting point of Cabozantinib (S)-Malate is approximately 150-160°C, which is favorable for stability during storage and handling.
      - Stability: The compound is stable under normal laboratory conditions, making it suitable for long-term storage and use in various formulations.
      - Reactivity: As a multi-kinase inhibitor, Cabozantinib (S)-Malate interacts with specific biological targets, which is essential for its therapeutic effects.

      advantage

      1. Efficacy in Cancer Treatment: Its ability to inhibit multiple pathways involved in tumor growth and metastasis makes it a powerful agent in oncology.

      2. Improved Bioavailability: The malate salt form enhances solubility, which can lead to better absorption and efficacy in clinical applications.

      3. Research Versatility: Cabozantinib (S)-Malate is suitable for a wide range of research applications, including preclinical and clinical studies, making it a valuable tool for researchers.

      4. Cost-Effectiveness: By utilizing this compound, pharmaceutical companies can develop effective treatments while optimizing production costs.

      Laboratory Equipment and Supplies

      To facilitate the effective use of Cabozantinib (S)-Malate, we offer a range of laboratory equipment and supplies that are compatible with this compound. Our offerings include:

      - High-Performance Liquid Chromatography (HPLC) Systems: Essential for analyzing the purity and concentration of Cabozantinib (S)-Malate in various formulations.
      - Mass Spectrometry (MS) Equipment: Ideal for determining the molecular weight and structure of the compound, ensuring accurate characterization.
      - Reagents and Solvents: A comprehensive selection of high-quality reagents and solvents to support experiments and formulations involving Cabozantinib (S)-Malate.
      - Safety Equipment: Personal protective equipment (PPE) and laboratory safety supplies to ensure safe handling and usage of the compound.

      conclusion

      Cabozantinib (S)-Malate is a potent and versatile compound with significant applications in cancer research and treatment. Its unique properties and advantages make it an essential addition to any pharmaceutical or research laboratory.

      As a reliable foreign trade company, we are committed to providing high-quality products and comprehensive support to help you succeed in your endeavors.

      Contact us today to learn more about how our Cabozantinib (S)-Malate can benefit your business and research initiatives.