EINECS: 205-285-7
Molecular Formula: C₄₇H₅₁NO₁₄
Synonyms: 7,11-methano-5h-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid deriv.; taxal; taxol a
Appearance: White Powder
Molecular Weight: 853.92
Density: 1.39g/cm³
Boiling Point: 957.115 °C at 760 mmHg
Melting Point: 213-216°C
Flash Point: 532.644 °C
Storage Temperature: 2-8°C
Refractive index: -49 ° (C=1, MeOH)
Solubility: solubile in methanol: 50 mg/mL, clear, colorless
Biological Activity: Antitumor agent; promotes and stabilizes tubulin polymerization, causing cell cycle arrest. Induces autocatalytic activation of caspase-10 in CCRF-HSB-2 cells, triggering apoptosis.
Stability: Stable. Incompatible with strong oxidizing agents. Combustible.
Usage: An antineoplastic. Used in the study of structure and function of microtubles into tubulin